Aycox’s sister-in-law, Susan Raab Ceklosky, confirmed the news on social media. A cause of death has not been shared, but Aycox was diagnosed with leukemia over a year ago. “She was definitely a fighter and everyone who knew her loved her,” Ceklosky said.
Supernatural and The Boys creator Eric Kripke said he was “gutted” to hear of Aycox’s passing in a remembrance shared on Twitter. “Too young,” Kripke wrote. “She was a delight & delivered lines like honey & venom. I marvel at how she made a simple word like ‘lackluster’ legendary.”
Gutted to hear the great #NickiAycox, our first #MegMasters, passed away. Too young. She was a delight & delivered lines like honey & venom. I marvel at how she made a simple word like ‘lackluster’ legendary. #RIP #SPN #SPNFamily @JensenAckles @jarpad pic.twitter.com/2xBK9rxs31— Eric Kripke (@therealKripke) November 20, 2022
Aycox portrayed demon and her human vessel Meg Masters in the first and fourth season of the CW’s Supernatural. Her last appearance on the series came in a season 5 episode through archival footage.
The actress also had recurring appearances in Providence, Ed, Over There, and Cold Case. Her other credits include Criminal Minds, Perfect Stranger, Dark Blue, The Girl on the Train, and Longmire. Aycox retired from acting after starring in the 2014 film Dead on Campus.
In recent years, Aycox acquired a following through her healthy eating and vegan lifestyle website Cashews and Olives. The former actress regularly shared updates about her leukemia journey via the Cashews and Olives Instagram.